Necropsy Tehnician 1- Req. 51931
For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
Independently perform necropsy functions and generate data on all types of studies. (i.e. basic/complex/specialized). Prepare and review documentation and perform quality control review of study data. Provide technical guidance, train, and serve as a mentor to less experienced staff. Contribute to department operations improvement in areas such as process development, SOP revisions, department inspections and equipment maintenance.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
- Independently perform specialized necropsy procedures (may include collection of tissues for special procedures, perfusion fixation, fetal evaluation, specialized dissection, neurodissection, bone densitometry collections, cerebral spinal fluid collections, embryo harvesting, etc.).
- Ensure raw data records are accurate, complete, and in appropriate order, and meet protocol specifications and/or GLP requirements. Review documentation of functions performed as part of quality control requirements. Prepare data forms for routine and specialized study procedures.
- Serve as lead/primary technician and independently perform necropsy functions and generate data on any type of study (i.e. basic/complex/specialized).
- Collect and record research data and biological specimens in compliance with Good Laboratory Practices Regulations (GLP), study protocols and SOP’s.
- Provide technical guidance, review data as generated/collected, and serve as a mentor to junior staff.
- Document, file, and address deviations and incidents through memoranda. Assist in preparing responses to both internal and external quality assurance audits.
- Review study protocols and provide recommendations to study director/supervisor on technical and logistical aspects of protocol design.
- Assist in training personnel in specialized techniques and study start up procedures requiring cross departmental interaction with all key study personnel
- May assume additional responsibilities that benefit the necropsy department (may include scheduling, training and sample shipments)
- Confirm necropsy abnormalities and gross observations
- Become trained in other laboratory departments in skill sets that can benefit that department.(may include fetal evaluations, cholinesterase evaluations, or other skills in the animal care, research or formulations departments)
- Evaluate department processes for possible improvements. Develop and standardize data collection procedures.
- Contribute to department operations improvement in areas such as process development, SOP revisions, department inspections, and equipment maintenance.
- Promote inter- and intra-departmental communication in order to facilitate and maximize performance associated with research projects.
- Retrieve and view Standard Operating Procedures using appropriate database.
- Use GLP’s, SOP’s, processes and company policies when performing all job functions.
- Perform all other related duties as assigned.
- Education: Bachelor’s degree (B.A./B.S.) or equivalent in a biological science .
- Experience: Minimum 3 years of necropsy laboratory experience or similar lab environment or must have fully satisfied technical and experience requirements for the previous level. GLP experience preferred.
- Knowledge of GLP’s and other federal regulations and guidelines relating to the care of laboratory animals preferred.
- An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
- Certification/Licensure: AALAS certification at the LAT level strongly preferred.
- Other: Demonstrate advanced technical and analytical skills. Effective communication and leadership skills. Ability to handle a variety of laboratory animals. Must be able to perform effectively as a team member, accurately record data, follow verbal and written instructions, maintain a positive work atmosphere, communicate effectively, and interact in a professional manner with management, coworkers, and sponsors. Proficient in the operation of data collection equipment. Understanding of basic, intermediate, and complex study design and protocols. Ability to organize and prioritize work to meet deadlines. Computer literacy including word processing, spreadsheet and database programs. Must be able to regularly make quick thinking decisions without affecting the integrity of the work being performed.
- Must be able to regularly perform laboratory procedures using appropriate laboratory instruments.
- Must be able to reach with hands and arms, working in spaces as narrow as 2 feet, while wearing safety equipment (PPE).
- Must be able to regularly communicate and exchange information with other personnel regarding all aspects of a study.
- Using fine motor skills must be able to regularly perform necropsy exams using forceps and scissors for approximately 8 hours a day. The exams require highly repetitive and extensive hand motions.
- Must be able to regularly perform repetitive necropsy-related tasks such as tying tags around fetuses and preparing fixative bottles for approximately 4-6 hours a day.
- Must be able to frequently observe physical attributes of species and changes thereto, including observations of fetuses via magnifying lens or microscope for approximately 6-8 hours a day...
- Must be able to regularly, firmly hold species in preparation for euthanasia.
- Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.
- Regularly operate a computer and other office productivity machinery, such as a calculator, copy machine, and computer printer.
- Regularly record data by hand or on a computer terminal.
- Regularly stand approximately 4 to 6 hours a day.
- Employees must be able to lift, move, manipulate, and/or hold heavy objects up to and including 50 pounds; this includes work materials, equipment, and/or animals.
- Must be able to frequently manipulate and remove objects from shelves one and one half to six and one half feet above the floor (with the aid of a step stool).
- Must be able to occasionally push wheeled carts weighing up to 1200 pounds.
- Must wear safety equipment according to OSHA regulations.
- Works in a research laboratory environment, which requires use of sharp objects, working around mechanical parts, working with or near known or unknown toxic or caustic chemicals and/or biological hazards, exposure to fumes and airborne particles, working at noise levels ranging from quiet to moderately noisy.
- The employee regularly works with haired animals with risk of exposure to allergens, zoonotic disease, and biohazards.
- This position requires overtime, weekend, holiday and/or after hours shift coverage as needed.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities. About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.
Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.