Senior Research Scientist - Cardiology

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Who We Are:

We are a Boston based, MA biotech startup that is pioneering mRNA-modulating therapies to cure a broad range of genetic diseases. Our company is exploring the use of our novel platforms in neurological disorders, heart disease, and muscular dystrophies. 

Position summary:

We are seeking a highly skilled scientist with experience in in vivo and molecular/cellular biology to join their team. The ideal candidate will have extensive experience in in vivo and molecular/cellular biology of diseases (cardiovascular disease areas highly preferred), and design, execute and lead the in vivo studies in a fast-paced set up. This position requires an innovative mindset, and the ability to be self-driven, multi-tasking and work collaboratively to drive in vivo studies forward.

Key responsibilities for this position include:

• Drive (design, troubleshoot and execute) multiple in vivo studies: animal colony management, perform hands-on rodent in-life work (different routes of administration, surgeries, tissue collections, functional and behavior tests, etc.).  

• Design, troubleshoot and execute molecular assays (e.g., PCR, IHC, Western, MSD) in cell lines and rodent tissues.

• Manage a team of Research Associates.

• Manage external CROs for in vivo studies and cell-based studies.

• Collaborate with other teams across the organization to support data-driven decision-making.

• Communicate findings and results to a wide range of stakeholders in written and oral presentations, including senior management.

Preferred qualifications:

• A Ph.D. in pharmacology, cardiology, molecular/cellular biology, or a related discipline with 2- 5 years of post-graduate experience in research & development in a biotechnology or pharmaceutical setting.

• Extensive hands-on in vivo experience: animal colony management, hands-on rodent work experience (different routes of administration, surgeries, tissue collections, functional and behavior tests, etc.).  

• Experience with molecular and cellular techniques, hands-on experience with qPCR, ddPCR, Western Blot and immunocytochemistry and image analysis.

• Research background in cardiovascular therapeutic area is highly preferred.

• Experience managing junior team members. 

• Ability to work collaboratively in a fast-paced team environment, and to provide strategic direction to the team.

• Scientifically rigorous, self-driven, highly organized, with excellent oral and written communication skills.

The company is an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, national origin, disability status, protected veteran status or any other characteristic protected by law.